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Re: @Fünkchen: Johanniskraut...

Ludwig Müller schrieb am 1. März 2003 um 18:39 Uhr (486x gelesen):

Hab mal in PubMed gesucht und dir, wo vorhanden, den entsprechenden Teil aus dem Abstract rauskopiert. Es gibt noch eine ganze Menge mehr Literatur zu dem Thema.

J Pharm Pharmacol 2001 May;53(5):583-600, "St John's wort (Hypericum perforatum L.): a review of its chemistry, pharmacology and clinical properties.", Barnes J, Anderson LA, Phillipson JD.
"Concerns have been raised over interactions between St John's wort and certain prescribed medicines (including warfarin, ciclosporin, theophylline, digoxin, HIV protease inhibitors, anticonvulsants, selective serotonin reuptake inhibitors, triptans, oral contraceptives); advice is that patients taking these medicines should stop taking St John's wort, generally after seeking professional advice as dose adjustment of conventional treatment may be necessary."

Br J Clin Pharmacol 2002 Oct;54(4):349-56, "St John's wort (Hypericum perforatum): drug interactions and clinical outcomes.", Henderson L, Yue QY, Bergquist C, Gerden B, Arlett P.
"A number of clinically significant interactions have been identified with prescribed medicines including warfarin, phenprocoumon, cyclosporin, HIV protease inhibitors, theophylline, digoxin and oral contraceptives resulting in a decrease in concentration or effect of the medicines"

Br J Clin Pharmacol 2003 Jan;55(1):112-3, "Unwanted pregnancy on self-medication with St John's wort despite hormonal contraception.", Schwarz UI, Buschel B, Kirch W.

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